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Howard, Timothy
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Academic Article Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma.
Academic Article Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma.
Academic Article Genome-wide search for atopy susceptibility genes in Dutch families with asthma.
Academic Article Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein.
Academic Article Factor V Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease.
Academic Article Mapping susceptibility genes for allergic diseases.
Academic Article Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice.
Academic Article CLC-2 single nucleotide polymorphisms (SNPs) as potential modifiers of cystic fibrosis disease severity.
Academic Article Genome screen for asthma and bronchial hyperresponsiveness: interactions with passive smoke exposure.
Academic Article Effect of genetic variations in platelet glycoproteins Ibalpha and VI on the risk for coronary heart disease events in postmenopausal women taking hormone therapy.
Academic Article The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Academic Article Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.
Academic Article Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women.
Academic Article Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome.
Academic Article Evaluation of self-reported ethnicity in a case-control population: the stroke prevention in young women study.
Academic Article Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.
Academic Article Clinicopathologic characterization of naturally occurring diabetes mellitus in vervet monkeys.
Academic Article Estrogen receptor polymorphisms and the vascular effects of hormone therapy.
Academic Article Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys.
Academic Article Importance of hedgehog interacting protein and other lung function genes in asthma.
Academic Article Common variants in the periostin gene influence development of atherosclerosis in young persons.
Academic Article Job activities and respiratory symptoms among farmworkers in North Carolina.
Academic Article Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
Academic Article Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.
Academic Article Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
Academic Article Increased corpus callosum volume in children with chromosome 22q11.2 deletion syndrome is associated with neurocognitive deficits and genetic polymorphisms.
Academic Article Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysis.
Academic Article Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA).
Academic Article D20S16 is a complex interspersed repeated sequence: genetic and physical analysis of the locus.
Academic Article Genotype-phenotype correlation for nucleotide substitutions in the IgII-IgIII linker of FGFR2.
Academic Article Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy.
Academic Article Association of autoimmune thyroid disease with a microsatellite marker for the thyrotropin receptor gene and CTLA-4 in a Japanese population.
Academic Article Autosomal dominant postaxial polydactyly, nail dystrophy, and dental abnormalities map to chromosome 4p16, in the region containing the Ellis-van Creveld syndrome locus.
Academic Article Genetics of allergy and bronchial hyperresponsiveness.
Academic Article Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations.
Academic Article Major genes regulating total serum immunoglobulin E levels in families with asthma.
Academic Article Association of a promoter polymorphism of the CD14 gene and atopy.
Academic Article Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population.
Academic Article Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease.
Academic Article Major recessive gene(s) with considerable residual polygenic effect regulating adult height: confirmation of genomewide scan results for chromosomes 6, 9, and 12.
Academic Article Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28.
Academic Article Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations.
Academic Article Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma.
Academic Article A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects.
Academic Article Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel.
Academic Article Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
Academic Article Genomewide screen for pulmonary function in 200 families ascertained for asthma.
Academic Article Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women.
Academic Article Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma.
Academic Article Cognitive correlates of a functional COMT polymorphism in children with 22q11.2 deletion syndrome.
Academic Article Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes.
Academic Article Association of polymorphisms in CASP10 and CASP8 with FEV(1)/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics.
Academic Article Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study.
Academic Article Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness.
Academic Article Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.
Academic Article COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome.
Academic Article Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.
Academic Article Epigenetic changes with dietary soy in cynomolgus monkeys.
Academic Article Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.
Academic Article The C11orf30-LRRC32 region is associated with total serum IgE levels in asthmatic patients.
Academic Article The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.
Academic Article Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
Academic Article Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome.
Academic Article D20S213, a microsatellite polymorphism near the D20S16 locus.
Academic Article Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): reassignment to human chromosome 12q.
Academic Article Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome.
Academic Article Genetic heterogeneity of Saethre-Chotzen syndrome, due to TWIST and FGFR mutations.
Academic Article Fluorescent allele-specific PCR (FAS-PCR) improves the reliability of single nucleotide polymorphism screening.
Academic Article A physical map of the 20q12-q13.1 region associated with type 2 diabetes.
Academic Article Mapping susceptibility genes for asthma and allergy.
Concept Organ Size
Concept Respiratory Sounds
Concept Adaptor Proteins, Signal Transducing
Concept Smoking
Concept Schizophrenia
Concept Longitudinal Studies
Concept STAT4 Transcription Factor
Concept DNA, Satellite
Concept Psychiatric Status Rating Scales
Concept Tobacco Smoke Pollution
Concept Sex Factors
Concept Lod Score
Concept Scavenger Receptors, Class B
Concept Sequence Alignment
Concept Genome, Human
Concept Smoke
Concept Transcription Initiation Site
Concept Syndrome
Concept Genes
Concept Ellis-Van Creveld Syndrome
Concept Amino Acid Sequence
Concept Sexual Maturation
Concept Cohort Studies
Concept Seasons
Concept Stroke
Concept src-Family Kinases
Concept Skin Tests
Concept E-Selectin
Concept Genetic Loci
Concept Genome
Concept Intracellular Signaling Peptides and Proteins
Concept Statistics, Nonparametric
Concept Lung Diseases
Concept Organ Specificity
Concept Regulatory Sequences, Nucleic Acid
Concept Retrospective Studies
Concept Sequence Deletion
Concept Neoplasm Regression, Spontaneous
Concept Multicenter Studies as Topic
Concept Models, Statistical
Concept Consensus Sequence
Concept Signal Transduction
Concept Nitric Oxide Synthase Type III
Concept Lung
Concept Severity of Illness Index
Concept Microscopy, Electron, Scanning
Concept Gene Expression Profiling
Concept Tandem Mass Spectrometry
Concept Blotting, Southern
Concept Saliva
Concept Nutrition Surveys
Concept Soybean Proteins
Concept Sequence Analysis, DNA
Concept Patient Selection
Concept Saint Kitts and Nevis
Concept Lung Neoplasms
Concept Data Interpretation, Statistical
Concept Genetic Association Studies
Concept Software
Concept Multigene Family
Concept DiGeorge Syndrome
Concept Sequence Tagged Sites
Concept Epistasis, Genetic
Concept Polymorphism, Single Nucleotide
Concept Death, Sudden, Cardiac
Concept Receptors, Cell Surface
Concept Genes, Dominant
Concept Quantitative Trait Loci
Concept Case-Control Studies
Concept Social Behavior
Concept Mice, Inbred Strains
Concept Prospective Studies
Concept Cross-Sectional Studies
Concept Sequence Homology, Amino Acid
Concept Stress, Psychological
Concept Sequence Homology, Nucleic Acid
Concept Genome-Wide Association Study
Concept Oligonucleotide Array Sequence Analysis
Concept United States
Concept Sex Characteristics
Concept Southeastern United States
Concept Serine
Concept Lupus Erythematosus, Systemic
Concept In Situ Hybridization, Fluorescence
Concept Schizophrenic Psychology
Concept Base Sequence
Concept Alleles
Concept Genes, Recessive
Concept Follow-Up Studies
Concept Genes, Homeobox
Concept Molecular Sequence Data
Concept Tumor Suppressor Proteins
Concept Heart Septal Defects, Ventricular
Academic Article A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Academic Article Occupational health outcomes for workers in the agriculture, forestry and fishing sector: implications for immigrant workers in the southeastern US.
Academic Article Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
Academic Article Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population.
Academic Article Recruiting underserved mothers to medical research: findings from North Carolina.
Academic Article Methylomics of gene expression in human monocytes.
Academic Article Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.
Academic Article Lifetime and current pesticide exposure among Latino farmworkers in comparison to other Latino immigrants.
Academic Article DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.
Academic Article Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.
Academic Article Learning Ability as a Function of Practice: Does It Apply to Farmworkers?
Academic Article The RBMX gene as a candidate for the Shashi X-linked intellectual disability syndrome.
Academic Article Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.
Academic Article DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis.
Academic Article Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article Urinary Cotinine Levels Among Latino Tobacco Farmworkers in North Carolina Compared to Latinos Not Employed in Agriculture.
Academic Article The Role of Copy Number Variation in African Americans with Type 2 Diabetes-Associated End Stage Renal Disease.
Academic Article Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer.
Academic Article Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques.
Academic Article Brain Anatomy in Latino Farmworkers Exposed to Pesticides and Nicotine.
Academic Article Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer.
Academic Article Changes in DNA methylation over the growing season differ between North Carolina farmworkers and non-farmworkers.
Academic Article "He Beat You in the Blood": Knowledge and Beliefs About the Transmission of Traits Among Latinos from Mexico and Central America.
Academic Article Organophosphate Pesticide Urinary Metabolites Among Latino Immigrants: North Carolina Farmworkers and Non-farmworkers Compared.
Academic Article The impacts of pesticide and nicotine exposures on functional brain networks in Latino immigrant workers.
Academic Article Farmworker and nonfarmworker Latino immigrant men in North Carolina have high levels of specific pesticide urinary metabolites.
Academic Article Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
Academic Article Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.
Academic Article Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster.
Academic Article Transancestral mapping and genetic load in systemic lupus erythematosus.
Academic Article Pesticide Urinary Metabolites Among Latina Farmworkers and Nonfarmworkers in North Carolina.
Academic Article Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression.
Academic Article Proteomic Architecture of Human Coronary and Aortic Atherosclerosis.
Academic Article CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools.
Academic Article Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis.
Academic Article Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes.
Academic Article Estradiol Treatment Initiated Early After Ovariectomy Regulates Myocardial Gene Expression and Inhibits Diastolic Dysfunction in Female Cynomolgus Monkeys: Potential Roles for Calcium Homeostasis and Extracellular Matrix Remodeling.
Academic Article Monocyte Polarization is Altered by Total-Body Irradiation in Male Rhesus Macaques: Implications for Delayed Effects of Acute Radiation Exposure.
Academic Article Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review.
Grant Integrated Omics Analysis of Pain: Omics Data Generation Center
Academic Article Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans.
Academic Article "It's Worse to Breathe It Than to Smoke It": Secondhand Smoke Beliefs in a Group of Mexican and Central American Immigrants in the United States.
Academic Article The Need for Multi-Omics Biomarker Signatures in Precision Medicine.
Academic Article FADS genetic and metabolomic analyses identify the ?5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids.
Academic Article Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial.
Academic Article Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
Academic Article Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies.
Academic Article Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting.
Academic Article Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model.
Academic Article Efficiency of whole-exome sequencing in old world and new world primates using human capture reagents.
Academic Article Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries.
Grant Development of a Wake Forest Multi-Species NHP Biorepository to Support Interdisciplinary Aging Studies
Academic Article Mental models about heredity among immigrant Latinx adults with limited education from Mexico and Central America.
Academic Article Genetic Knowledge and Communication Among Mexican Farmworkers and Non-farmworkers in North Carolina.
Academic Article Salivary dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus.
Academic Article Multi-Site Observational Study to Assess Biomarkers for Susceptibility or Resilience to Chronic Pain: The Acute to Chronic Pain Signatures (A2CPS) Study Protocol.
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